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Cardiac tissue engineering: Multiple approaches and potential applications

3 Oct 2022

Abstract excerpt

The overall increase in cardiovascular diseases and, specifically, the ever-rising exposure to cardiotoxic compounds has greatly increased in vivo animal testing; however, mainly due to ethical concerns related to experimental animal models, there is a strong interest in new in vitro models focused on the human heart. In recent years, human pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs) emerged as...

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PMID: 36263357
DOI: 10.3389/fbioe.2022.980393

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