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Generation and Maturation of Human iPSC-derived Cardiac Organoids in Long Term Culture

2022-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Cardiovascular diseases remain the leading cause of death worldwide; hence there is an increasing focus on developing physiologically relevant in vitro cardiovascular tissue models suitable for studying personalized medicine and pre-clinical tests. Despite recent advances, models that reproduce both tissue complexity and maturation are still limited. We have established a scaffold-free protoco...

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Literature Corpus work
b1109d80-2fac-552b-b0ce-1ae378a9c711
DOI
10.1101/2022.03.07.483273
Open publication

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