Article

Cohort-Based Association Study Association of Genetic Variations of ABCC with the Non-Response and Relapse of Pediatric Patients with Central Nervous System Tumors

2025-05-29

Abstract excerpt

<h4>Objectives: </h4> The variability in outcomes among individuals is caused by multiple factors, including genetic variations in drug transporter genes known as ABCs. This study investigates the clinical impact of single nucleotide variants (SNV) in the ABCC1/MRP1, ABCC2/MRP2, and ABCC4/MRP4 genes on the clinical response and relapse of pediatric patients with central nervous system tumors. <h4>Methods:</h4> In...

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Literature Corpus work: 7902bcc4-99f5-5717-a320-8a70ef94aed9
DOI: 10.20944/preprints202505.2354.v1

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