Article
Drug-resistance in central nervous system tumors: from the traditional cell-resistance model to the genetically driven approaches on therapy.
Current pharmaceutical biotechnology - 1 Apr 2007
Valera E T, Machado H R, Scrideli C A, Lucio-Eterovic A K, Tone L G
Abstract excerpt
The advances in the cure rates observed in the oncology field in the past decades were not fully assembled by primary brain tumors. In this heterogeneous group of diseases, resistance to either chemotherapy or radiotherapy still is a major problem to be addressed. Several genetic and epigenetic events may directly influence the response to treatment in these tumors. Throughout recent discoveries, drug resistance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.