Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

28 Jul 2011

Abstract excerpt

BACKGROUND: Although the prognostic value of the ATP-binding cassette, subfamily C (ABCC) transporters in childhood neuroblastoma is usually attributed to their role in cytotoxic drug efflux, certain observations have suggested that these multidrug transporters might contribute to the malignant phenotype independent of cytotoxic drug efflux. METHODS: A v-myc myelocytomatosis viral related oncogene, neuroblastoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Drug Transport and Resistance Mechanisms
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21799180
DOI: 10.1093/jnci/djr256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug EffluxPMID 21799180Read ↗

Therapy resistance in neuroblastoma: Mechanisms and reversal strategiesSemantic proximity Read ↗

CHL1gene acts as a tumor suppressor in human neuroblastomaSemantic proximity Read ↗

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastomaSemantic proximity Read ↗

Factors Influencing Mortality in Children with Central Nervous System Tumors: A Cohort Study on Clinical Characteristics and Genetic Markers.Semantic proximity Read ↗

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.Semantic proximity Read ↗

In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and MetastasisSemantic proximity Read ↗

The Novel Bcl-2 Inhibitor ABT-737 Is More Effective in Hypoxia and Is Able to Reverse Hypoxia-Induced Drug Resistance in Neuroblastoma CellsSemantic proximity Read ↗

Cohort-Based Association Study Association of Genetic Variations of ABCC with the Non-Response and Relapse of Pediatric Patients with Central Nervous System TumorsSemantic proximity Read ↗

BIOLOGY AND TREATMENT OF NEUROBLASTOMASemantic proximity Read ↗

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastomaSemantic proximity Read ↗

The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitroSemantic proximity Read ↗

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.