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Article

Factors Influencing Mortality in Children with Central Nervous System Tumors: A Cohort Study on Clinical Characteristics and Genetic Markers.

Genes - 9 Apr 2024

Torres-Espíndola Luz María, Pérez-De Marcos Juan Carlos, Castillejos-López Manuel, Velasco-Hidalgo Liliana, Cárdenas-Cardós Rocío, De Uña-Flores Armando, Salinas-Lara Citlaltepetl, Caballero-Salazar Silvia, Fernández-Plata Rosario, Aquíno-Gálvez Arnoldo

Abstract excerpt

Multidrug resistance (MDR) commonly leads to cancer treatment failure because cancer cells often expel chemotherapeutic drugs using ATP-binding cassette (ABC) transporters, which reduce drug levels within the cells. This study investigated the clinical characteristics and single nucleotide variant (SNV) in ABCB1, ABCC1, ABCC2, ABCC4, and ABCG2, and their association with mortality in pediatric patients with...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38674407
DOI: 10.3390/genes15040473
PMCID: PMC11050576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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