Article

Excitatory inhibitory imbalance underlies hippocampal atrophy in individuals with 22q11.2 Deletion Syndrome with psychotic symptoms

2022-09-06

Abstract excerpt

<h4>Background</h4> Abnormal neurotransmitter levels have been reported in subjects at high risk for schizophrenia, leading to a shift in the excitatory/inhibitory balance. However, it is unclear if these alterations are predating the onset of clinically relevant symptoms. Our aim was to explore in vivo measures of excitatory/inhibitory balance in 22q11.2 deletion carriers, a population at high genetic risk for ps...

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Literature Corpus work: 78fe11f7-cde3-53b5-a328-c2a0eb1efa48
DOI: 10.1101/2022.09.06.22279580

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