Article
A multistage, dual voxel study of glutamate in the anterior cingulate cortex in schizophrenia supports a primary pyramidal dysfunction model of disorganization
2023-11-28
Abstract excerpt
<h4>Background</h4> Schizophrenia is an illness where glutamatergic dysfunction in the anterior cingulate cortex (ACC) has been long suspected; Recent in vivo evidence (Adams et al. 2022) has implicated pyramidal dysfunction (reduced glutamate tone) as the primary pathophysiology contributing to subtle features, with a secondary disinhibition effect (higher glutamate tone) resulting in the later emergence of prom...
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Identifiers and source
- Literature Corpus work
- 283d2895-83fd-5a90-a018-c835b86bf940
- DOI
- 10.1101/2023.11.27.568930