Article
Cortico-Striatal GABAergic and Glutamatergic Dysregulations in Subjects at Ultra-High Risk for Psychosis Investigated with Proton Magnetic Resonance Spectroscopy.
The international journal of neuropsychopharmacology - 12 Sept 2015
de la Fuente-Sandoval Camilo, Reyes-Madrigal Francisco, Mao Xiangling, León-Ortiz Pablo, Rodríguez-Mayoral Oscar, Solís-Vivanco Rodolfo, Favila Rafael, Graff-Guerrero Ariel, Shungu Dikoma C
Abstract excerpt
BACKGROUND: Dysregulations of the major inhibitory and excitatory amino neurotransmitter systems of γ-aminobutyric acid and glutamate, respectively, have been described in patients with schizophrenia. However, it is unclear whether these abnormalities are present in subjects at ultra-high risk for psychosis. METHODS: Twenty-three antipsychotic naïve subjects at ultra-high risk and 24 healthy control subjects,...
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