Article

UDP-Glucose 6-Dehydrogenase Knockout Impairs Migration and Decreases <i>in vivo</i> Metastatic Ability of Breast Cancer Cells

2020-05-31

Abstract excerpt

<h4>ABSTRACT</h4> Dysregulated metabolism is a hallmark of cancer that supports tumor growth and metastasis. One understudied aspect of cancer metabolism is altered nucleotide sugar biosynthesis, which drives aberrant cell surface glycosylation known to support various aspects of cancer cell behavior including migration and signaling. We examined clinical association of nucleotide sugar pathway gene expression an...

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Literature Corpus work: 789b9c75-e943-59ce-bb78-87ac3a562730
DOI: 10.1101/2020.05.30.125419

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