Article

Breast cancer N Glycosylation dysregulation driven by mutations modulates chemotherapy response and macrophage immunosuppression

2025-07-15

Abstract excerpt

<title>Abstract</title> <p>Metabolic reprogramming plays a key role in breast cancer progression, but its underlying mechanisms and clinical relevance remain poorly understood. This study integrated multi-omics data from 1,086 breast tumors and 99 normal tissues (TCGA/GEO databases) through combined transcriptomic and single-cell sequencing analyses, pioneering the demonstration of the central regulatory role of...

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Literature Corpus work: 1d358d69-37c1-5a36-b84a-b013e5ff3c17
DOI: 10.21203/rs.3.rs-6950007/v1

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