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Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors

2020-12-10

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<title>Abstract</title> <p><bold>Background</bold>Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling and cell and gene therapies. Their potential, however, has been bottlenecked in a mostly laboratory setting due to bioprocess challenges in the scale-up of large quantities of high-quality cells for...

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Literature Corpus work
65b35013-621e-570c-b4e6-367177799720
DOI
10.21203/rs.3.rs-63517/v2
Open publication

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