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Whole-transcriptomic profiling of human cerebral cortex tissues reveals microglia-associated molecular subtypes

2022-05-20

Abstract excerpt

Microglia is one of the major immune cell types in the human brain and plays pivotal roles in regulating inflammatory and immune response in healthy as well as disease states. By analyzing whole transcriptomic data derived from a large cohort of postmortem cortex tissues, we identified two distinct microglial subtypes within the population. The main difference between the two subtypes lies in the differential expr...

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Identifiers and source

Literature Corpus work
6db314e3-654c-58e3-8224-f7465674dece
DOI
10.1101/2022.05.19.492569
Open publication

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Whole-transcriptomic profiling of human cerebral cortex tissues reveals microglia-associated molecular subtypesDOI 10.1101/2022.05.19.492569
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