Article

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation

2023-01-15

Abstract excerpt

Long-read sequencing technologies substantially overcome the limitations of short-reads but to date have not been considered as feasible replacement at scale due to a combination of being too expensive, not scalable enough, or too error-prone. Here, we develop an efficient and scalable wet lab and computational protocol for Oxford Nanopore Technologies (ONT) long-read sequencing that seeks to provide a genuine alt...

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Literature Corpus work: 435016d7-4f3f-510f-a37f-47b76aebd506
DOI: 10.1101/2023.01.12.523790

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