Article

The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor

2025-02-07

Abstract excerpt

1. <h4>Background</h4> Transcription factor 4 (TCF4) is a member of the basic helix-loop-helix (bHLH) family of transcription factors and guides proper embryogenesis, particularly neurogenesis, myogenesis, heart development and hematopoiesis. bHLH proteins exhibit variations in length, expression patterns and the presence of defined motifs. The interaction of TCF4 with DNA is dependent on the presence of a conser...

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Literature Corpus work: 77f28c21-6a22-5555-88af-e1e6c78f0e16
DOI: 10.1101/2025.02.06.636797

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