Article

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

2021-02-10

Abstract excerpt

<h4>ABSTRACT</h4> Exposure to a pathogen elicits an adaptive immune response aimed to control and eradicate. Interrogating the abundance and specificity of the naive B cell repertoire contributes to understanding how to potentially elicit protective responses. Here, we isolated naive B cells from 8 seronegative human donors targeting the SARS-CoV-2 receptor-binding domain (RBD). Single B cell analysis showed dive...

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Literature Corpus work: 77bd7389-d97c-504e-87dc-b6cbd7e98ad9
DOI: 10.1101/2021.02.02.429458

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