Article

A public antibody class recognizes a novel S2 epitope exposed on open conformations of SARS-CoV-2 spike

2021-12-03

Abstract excerpt

Delineating the origins and properties of antibodies elicited by SARS-CoV-2 infection and vaccination is critical for understanding their benefits and potential shortcomings. Therefore, we investigated the SARS-CoV-2 spike (S)-reactive B cell repertoire in unexposed individuals by flow cytometry and single-cell sequencing. We found that ∼82% of SARS-CoV-2 S-reactive B cells show a naive phenotype, which represents...

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Literature Corpus work: 0b74d718-602f-550f-8858-f3f5e3d8ceda
DOI: 10.1101/2021.12.01.470767

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