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Serum proteomics reveals high-affinity and convergent antibodies by tracking SARS-CoV2 hybrid immunity to emerging variants of concern

2024-10-03

Abstract excerpt

The rapid spread of SARS-CoV2 and continuing impact on human health has prompted the need for effective and rapid development of monoclonal antibody therapeutics. In this study, we interrogate polyclonal antibodies in serum and B cells from whole blood of three donors with SARS-CoV2 immunity to find high-affinity anti-SARS-CoV2 antibodies to escape variants. Serum IgG antibodies were selected by affinity to the re...

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Identifiers and source

Literature Corpus work
2611ffd2-ecf9-52dc-ad38-018f848b8e15
DOI
10.1101/2024.10.02.616394
Open publication

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