Article

No substantial pre-existing B cell immunity against SARS-CoV-2 in healthy adults

2021-09-08

Abstract excerpt

<h4>Summary</h4> Pre-existing immunity against SARS-CoV-2 may have critical implications for our understanding of COVID-19 susceptibility and severity. Various studies recently provided evidence of pre-existing T cell immunity against SARS-CoV-2 in unexposed individuals. In contrast, the presence and clinical relevance of a pre-existing B cell immunity remains to be fully elucidated. Here, we provide a detailed a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e3496f80-bf12-52a5-a868-a07449a90efd
DOI: 10.1101/2021.09.08.459398

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

No substantial pre-existing B cell immunity against SARS-CoV-2 in healthy adultsDOI 10.1101/2021.09.08.459398Read

S protein-reactive IgG and memory B cell production after human SARS-CoV-2 infection includes broad reactivity to the S2 subunitSemantic proximity Read

Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patientsSemantic proximity Read

SARS-CoV-2 specific memory B-cells from individuals with diverse disease severities recognize SARS-CoV-2 variants of concernSemantic proximity Read

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecovirusesSemantic proximity Read

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecovirusesSemantic proximity Read

Innate and Adaptive Immune Responses to SARS-CoV-2 in Humans: Relevance to Acquired Immunity and Vaccine ResponsesSemantic proximity Read

Prolonged evolution of the human B cell response to SARS-CoV-2 infectionSemantic proximity Read

Persistence of Functional Memory B Cells Recognizing SARS-CoV-2 Variants Despite Loss of Specific IgGSemantic proximity Read

SARS-CoV-2 reactive T cells in uninfected individuals are likely expanded by beta-coronavirusesSemantic proximity Read

An Overview of the Immune Response to COVID-19 Vaccination and Strategies to Boost SARS-CoV-2 Immunity in People with Inborn Errors of ImmunitySemantic proximity Read

The T cell immune response against SARS-CoV-2.Semantic proximity Read

Observational Report on Functional SARS-CoV-2 Immune Responses in Immune Competent and Compromised IndividualsSemantic proximity Read