Article

TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling

2023-09-05

Abstract excerpt

Chromosomal instability (CIN) is a hallmark of cancer aggressiveness, providing genetic plasticity and tumor heterogeneity that allows the tumor to evolve and adapt to stress conditions. CIN is considered a cancer therapeutic biomarker because healthy cells do not exhibit CIN. Despite recent efforts to identify therapeutic strategies related to CIN, the results obtained have been very limited. CIN is characterized...

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Literature Corpus work: 77a8483a-5055-5463-ab93-d768afc92505
DOI: 10.1101/2023.09.04.556165

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