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Article

RCC2 promotes breast cancer progression through regulation of Wnt signaling and inducing EMT

1 Jan 2019

Abstract excerpt

Regulator of chromosome condensation 2 (RCC2), also known as TD-60, is an RCC1 family member and plays an essential role in mitosis. However, the roles of RCC2 in breast cancer are still unclear. In this study, RCC2 was found to exert oncogenic activities in breast cancer. Samples of breast cancer tissue revealed an increased level of RCC2 and a high level of RCC2 was associated with poor overall survival rate of...

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PMID: 31839818
DOI: 10.7150/jca.36430

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