Article

OKseqHMM: a genome-wide replication fork directionality analysis toolkit

2022-01-13

Abstract excerpt

<h4>Motivation</h4> During each cell division, tens of thousands of DNA replication origins are coordinately activated to ensure the complete duplication of the entire human genome. However, the progression of replication forks can be challenged by numerous factors. One such factor is transcription-replication conflicts (TRC), which can either be co-directional or head-on with the latter being revealed as more da...

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Literature Corpus work: 7795268c-5baf-503e-82dd-07584c6111bf
DOI: 10.1101/2022.01.12.476022

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