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Genome-Wide Meta-Analysis of Late-Onset Alzheimer’s Disease Using Rare Variant Imputation in 65,602 Subjects Identifies Novel Rare Variant Locus <i>NCK2</i>: The International Genomics of Alzheimer’s Project (IGAP)

2021-03-24

Abstract excerpt

Risk for late-onset Alzheimer’s disease (LOAD) is driven by multiple loci primarily identified by genome-wide association studies, many of which are common variants with minor allele frequencies (MAF)> 0.01. To identify additional common and rare LOAD risk variants, we performed a GWAS on 25,170 LOAD subjects and 41,052 cognitively normal controls in 44 datasets from the International Genomics of Alzheimer’s Proje...

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Literature Corpus work: 775130cd-befd-5fa8-9d9b-62696e29bec4
DOI: 10.1101/2021.03.14.21253553

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Genome-Wide Meta-Analysis of Late-Onset Alzheimer’s Disease Using Rare Variant Imputation in 65,602 Subjects Identifies Novel Rare Variant Locus <i>NCK2</i>: The International Genomics of Alzheimer’s Project (IGAP)DOI 10.1101/2021.03.14.21253553Read

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