Article

Transposable elements drive species-specific and tissue-specific transcriptomes in human development

2025-05-23

Abstract excerpt

<h4>Background: </h4> Transposable elements (TEs) are an abundant and crucial regulatory resource in the human genome. Serving as alternative promoters, TEs can be reactivated and produce TE-initiated transcripts, which play importance roles in early development and differentiated tissues. However, the prevalence and function of TE-initiated transcription in human development are poorly characterized. <h4>Results:...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9deac769-b915-569b-9aa5-867aebcf38e5
DOI: 10.1101/2025.05.19.654775

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transposable elements drive species-specific and tissue-specific transcriptomes in human developmentDOI 10.1101/2025.05.19.654775Read

Transposable elements generate regulatory novelty in a tissue-specific fashionSemantic proximity Read

Regulatory Transposable Elements in the Encyclopedia of DNA ElementsSemantic proximity Read

Role of Transposable Elements in Gene Regulation in the Human GenomeSemantic proximity Read

Atlas of transcriptionally active transposable elements in human adult tissuesSemantic proximity Read

Expression spectrum of TE-derived transcripts in human adult tissuesSemantic proximity Read

Intrinsically linked lineage specificity of transposable elements, lncRNA genes, and transcriptional regulationSemantic proximity Read

Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genomeSemantic proximity Read

Differential expression of transposable elements in stem cell lineages of the preimplantation embryoSemantic proximity Read

The impact of transposable elements on mammalian development.Semantic proximity Read

Genome-wide analysis of the association of transposable elements with gene regulation suggests that <i>Alu</i> elements have the largest overall regulatory impactSemantic proximity Read

Dynamic regulation of a domesticated DNA transposon-derived gene in human germline and early embryonic developmentSemantic proximity Read

Transposable elements as tissue-specific enhancers in cancers of endodermal lineageSemantic proximity Read