Article

Influenza A virus avian-derived PB1 gene has evolved to match its codon usage to interferon-altered human tRNA pools

2017-06-01

Abstract excerpt

Influenza A viruses cause an annual highly contagious respiratory disease in humans, and are responsible for periodic human pandemics that have high mortality rates. Pandemic influenza A viruses can result from reassortment of one or more gene segments between a human and an avian virus. These avian virus gene segments need to adapt to humans post introduction. The role of synonymous mutations in this adaptation i...

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Literature Corpus work: 7706b754-5e6e-518a-95f1-cda0869b6431
DOI: 10.7287/peerj.preprints.3000v1

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