Article

Comprehensive mapping of avian influenza polymerase adaptation to the human host

2019-01-04

Abstract excerpt

<h4>Summary</h4> Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. However, it is unclear if these mutations represent all ways that influenza can adapt to a new host. Here we take a prospective approach to this question by completely mapping amino-acid mutation...

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Literature Corpus work: 7b455001-4389-51e6-bc12-54406f95f8b6
DOI: 10.1101/512525

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