Article

Focal adhesion kinase promotes metastasis in BRAF-mutant melanoma

2026-03-21

Abstract excerpt

Despite the availability of several FDA-approved therapies, metastatic melanoma remains a significant clinical challenge, particularly for patients with brain metastases, which frequently represent the site of treatment failure and a major cause of melanoma-related mortality. Melanoma exhibits a strong propensity to metastasize to the brain, yet the molecular mechanisms driving this lethal progression remain incom...

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Literature Corpus work: 76f70a33-f303-5723-bbf9-d3fb60ba2de4
DOI: 10.64898/2026.03.19.712212

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