Article
Focal adhesion kinase signaling and the aggressive melanoma phenotype.
Cell cycle (Georgetown, Tex.) - 1 Mar 2006
Hess Angela R, Hendrix Mary J C
Abstract excerpt
Focal adhesion kinase (FAK) mediates myriad cellular functions and has been found to be overexpressed in numerous human cancers. We recently explored the role of FAK in promoting the aggressive phenotype of melanoma cells, characterized by increased invasion, migration, and vasculogenic mimicry (...
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