Article

Copy number networks to guide combinatorial therapy for cancer and other disorders

2014-06-05

Abstract excerpt

<h4>ABSTRACT</h4> The dwindling drug pipeline is driving increased interest in the use of genome datasets to inform drug treatment. In particular, networks based on transcript data and protein-protein interactions have been used to design therapies that employ drug combinations. But there has been less focus on employing human genetic interaction networks constructed from copy number alterations (CNAs). These net...

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Literature Corpus work: 76ef035e-2c5a-5d5e-975a-170aaaa9d33a
DOI: 10.1101/005942

Open publication

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