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Article

Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care.

Expert review of molecular diagnostics - 1 Jan 2010

Roukos Dimitrios H

Abstract excerpt

Although cancer heterogeneity, even within individual tumors with different treatment responses of subcloncal cells populations, suggests the need for personalized medicine, most funding and efforts go to conventional single gene-based research and comparative-effectiveness research. Cancer arises from changes in the DNA sequence in the genomes of cancer cells. These accelerating somatic mutations dysregulate...

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PMID: 20014921
DOI: 10.1586/erm.09.69

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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