Article

Induction of Bacteriophage PinR Facilitates the Evolution of Antibiotic Resistance

2022-03-29

Abstract excerpt

A recent work reports that the single treatment of β-lactams can cause a SOS-independent superfast evolution of multi-drug resistance in the DNA repair deficiency Escherichia coli ( E. coli ), but the mechanism is not yet clear. Here, we find that the induction of PinR, a lambdoid prophage Rac, is involved in this process and facilitates the evolution of antibiotic resistance in DNA repair deficiency bacteria th...

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Literature Corpus work: 76b109ba-ce64-55b0-9a09-4b8e2b123f45
DOI: 10.1101/2022.03.29.486199

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