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Article

Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli.

PLoS genetics - 1 Jul 2017

Moore Jessica M, Correa Raul, Rosenberg Susan M, Hastings P J

Abstract excerpt

Bacteria, yeast and human cancer cells possess mechanisms of mutagenesis upregulated by stress responses. Stress-inducible mutagenesis potentially accelerates adaptation, and may provide important models for mutagenesis that drives cancers, host pathogen interactions, antibiotic resistance and possibly much of evolution generally. In Escherichia coli repair of double-strand breaks (DSBs) becomes mutagenic, using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28727736
DOI: 10.1371/journal.pgen.1006733
PMCID: PMC5542668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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