Article

Genome recombination-mediated tRNA up-regulation conducts general antibiotic resistance of bacteria at early stage

2021-01-20

Abstract excerpt

Bacterial antibiotic resistance sets a great challenge to human health. It seems that the bacteria can spontaneously evolve resistance against any antibiotic within short time without the horizontal transfer of heterologous genes and before accumulating drug-resistant mutations. We have shown that the tRNA-mediated translational regulation counteracts the reactive oxygen species in bacteria. In this study, we demo...

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Literature Corpus work: 6d98069e-cd3a-5671-b866-affea3c1431b
DOI: 10.1101/2021.01.19.427372

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