Article
Roles of E. coli double-strand-break-repair proteins in stress-induced mutation.
DNA repair - 3 Feb 2006
He Albert S, Rohatgi Pooja R, Hersh Megan N, Rosenberg Susan M
Abstract excerpt
Special mechanisms of mutation are induced during growth-limiting stress and can generate adaptive mutations that permit growth. These mechanisms may provide improved models for mutagenesis in antibiotic resistance, evolution of pathogens, cancer progression and chemotherapy resistance. Stress-induced reversion of an Escherichia coli episomal lac frameshift allele specifically requires DNA...
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