Article
Oxidative stress drives mutagenesis through transcription coupled repair in bacteria
2022-06-28
Abstract excerpt
In bacteria, mutations lead to the evolution of antibiotic resistance, which is one the main public health problems of the 21 st century. Therefore, determining which cellular processes most frequently contribute to mutagenesis, especially in cells that have not been exposed to exogenous DNA damage, is critical. Here, we show that endogenous oxidative stress is a key driver of mutagenesis and the subsequent devel...
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Identifiers and source
- Literature Corpus work
- 9647951e-ddf8-504b-99c1-9600865313c0
- DOI
- 10.1101/2022.06.28.497968