Article

HSD2 neurons are evolutionarily conserved and required for aldosterone-induced salt appetite

2024-04-28

Abstract excerpt

Excessive aldosterone production increases the risk of heart disease, stroke, dementia, and death. Aldosterone increases both sodium retention and sodium consumption, and increased sodium consumption predicts end-organ damage in patients with aldosteronism. Preventing this increase may improve outcomes, but the behavioral mechanisms of aldosterone-induced sodium appetite remain unclear. In rodents, we identified a...

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Literature Corpus work: 76a2c167-9b52-5401-b1f6-cdd849378e33
DOI: 10.1101/2024.04.24.590990

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