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Identification of globin switching-related genes and RNAs via transcriptomic profiling of nucleated red blood cells isolated from the cord blood of preterm and full-term newborns 

2020-12-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> β-thalassemia and sickle cell disease (SCD) are chronic hemolytic anemias caused by mutation or deletion of the β-globin gene. Reactivation of fetal γ-globin gene (<italic>HBG</italic>) expression can ameliorate the clinical course of β-hemoglobinopathies. Our current understanding of the globin switching mechanism is not comprehensive, and research into the rol...

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Literature Corpus work
769dc4e0-1bf0-5473-b00d-aa709549fc13
DOI
10.21203/rs.3.rs-45443/v2
Open publication

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Identification of globin switching-related genes and RNAs via transcriptomic profiling of nucleated red blood cells isolated from the cord blood of preterm and full-term newborns&nbsp;DOI 10.21203/rs.3.rs-45443/v2
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