Identification of deregulated circular RNA circ-0008102 as novel biomarker in pediatric β-thalassemia patients

Abstract excerpt

<title>Abstract</title> <p>Circular RNA circ-0008102 has previously been found upregulated in β-thalassemia (β-thal) in circRNAs microarray. Our study aimed to identify whether circ-0008102 could be a novel biomarker in β-thal. qRT-PCR confirmed that the expression levels of circ-0008102 in pediatric β-thal patients with HbF ≥ 5.0% (n = 26) were significantly higher than that in pediatric β-thal patients with HbF...

Topics

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• beta-Thalassemia
• Cancer-related molecular mechanisms research
• China
• Gene Expression Profiling
• Gene Ontology
• Gene Regulatory Networks
• Oligonucleotide Array Sequence Analysis
• RNA, Long Noncoding

Identifiers and source

Literature Corpus work

50b291d8-5f29-5486-abb8-e65033e8ca26

DOI

10.21203/rs.3.rs-1984616/v1