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Article

Regulation of human fetal hemoglobin: new players, new complexities

19 Aug 2005

Abstract excerpt

The human globin genes are among the most extensively characterized in the human genome, yet the details of the molecular events regulating normal human hemoglobin switching and the potential reactivation of fetal hemoglobin in adult hematopoietic cells remain elusive. Recent discoveries demonstrate physical interactions between the beta locus control region and the downstream structural gamma- and beta-globin...

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Share to Epigenetics and DNA Methylation
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Identifiers

PMID: 16109777
DOI: 10.1182/blood-2005-05-2113

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