Article

Predicting the Immunogenicity of T cell epitopes: From HIV to SARS-CoV-2

2020-05-15

Abstract excerpt

We describe a physics-based learning model for predicting the immunogenicity of Cytotoxic T Lymphocyte (CTL) epitopes derived from diverse pathogens, given a Human Leukocyte Antigen (HLA) genotype. The model was trained and tested on experimental data on the relative immunodominance of CTL epitopes in Human Immunodeficiency Virus infection. The method is more accurate than publicly available models. Our model pred...

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Literature Corpus work: 764260ee-081a-56da-b6b6-b77c4a573ee0
DOI: 10.1101/2020.05.14.095885

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