Article

Prioritization of SARS-CoV-2 epitopes using a pan-HLA and global population inference approach

2020-04-01

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 T cell response assessment and vaccine development may benefit from an approach that considers the global landscape of the human leukocyte antigen (HLA) proteins. We predicted the binding affinity between 9-mer and 15-mer peptides from the SARS-CoV-2 peptidome for 9,360 class I and 8,445 class II HLA alleles, respectively. We identified 368,145 unique combinations of peptide-HLA comple...

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Literature Corpus work: dbb01691-a7b0-5fc6-882f-7c5d1a9b163e
DOI: 10.1101/2020.03.30.016931

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