Article

T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.

2024-10-24

Abstract excerpt

As SARS-CoV-2 variants continue to emerge capable of evading neutralizing antibodies, it has become increasingly important to fully understand the breadth and functional profile of T cell responses to determine their impact on the immune surveillance of variant strains. Here, sampling healthy individuals, we profiled the kinetics and polyfunctionality of T cell immunity elicited by mRNA vaccination. Modeling of an...

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Literature Corpus work: df183194-d840-5fce-86a6-4fa8c8ba88eb
DOI: 10.1101/2024.10.23.619918

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