Article

Predicted CTL responses from pressured epitopes in SARS-CoV-2 correlate with COVID-19 severity

2021-12-07

Abstract excerpt

Heterogeneity in susceptibility among individuals to COVID-19 has been evident through the pandemic worldwide. Protective cytotoxic T lymphocyte (CTL) responses generated against pathogens in certain individuals are known to impose selection pressure on the pathogen, thus driving emergence of new variants. In this study, we focus on the role played by host genetic heterogeneity in terms of HLA-genotypes in determi...

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Literature Corpus work: 1c5925ad-8ae3-53df-88b5-8dd3ab4043b4
DOI: 10.1101/2021.12.06.21267084

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