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Article

Predicted impact of the viral mutational landscape on the cytotoxic response against SARS-CoV-2.

PLoS computational biology - 1 Feb 2022

Foix Anna, López Daniel, Díez-Fuertes Francisco, McConnell Michael J, Martín-Galiano Antonio J

Abstract excerpt

The massive assessment of immune evasion due to viral mutations that increase COVID-19 susceptibility can be computationally facilitated. The adaptive cytotoxic T response is critical during primary infection and the generation of long-term protection. Here, potential HLA class I epitopes in the SARS-CoV-2 proteome were predicted for 2,915 human alleles of 71 families using the netMHCIpan EL algorithm. Allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35143484
DOI: 10.1371/journal.pcbi.1009726
PMCID: PMC8830725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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