Article
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes.
Genome medicine - 13 Aug 2020
Poran Asaf, Harjanto Dewi, Malloy Matthew, Arieta Christina M, Rothenberg Daniel A, Lenkala Divya, van Buuren Marit M, Addona Terri A, Rooney Michael S, Srinivasan Lakshmi, Gaynor Richard B
Abstract excerpt
BACKGROUND: The ongoing COVID-19 pandemic has created an urgency to identify novel vaccine targets for protective immunity against SARS-CoV-2. Early reports identify protective roles for both humoral and cell-mediated immunity for SARS-CoV-2. METHODS: We leveraged our bioinformatics binding prediction tools for human leukocyte antigen (HLA)-I and HLA-II alleles that were developed using mass spectrometry-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.