Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Landscape and selection of vaccine epitopes in SARS-CoV-2

14 Jun 2021

Abstract excerpt

BACKGROUND: T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding undesired effects such as antibody-dependent enhancement (ADE). METHODS: We explored the set of computationally predicted SARS-CoV-2 HLA-I and HLA-II ligands, examining protein source, concurrent human/murine coverage, and population coverage. Beyond MHC affinity, T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34127050
DOI: 10.1186/s13073-021-00910-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Landscape and selection of vaccine epitopes in SARS-CoV-2PMID 34127050Read ↗

Landscape and Selection of Vaccine Epitopes in SARS-CoV-2Semantic proximity Read ↗

Identification of promising SARS-CoV-2 CD8+ and CD4+ T cell epitopes by immunoinformatics approach for a multi-epitope-based vaccine designSemantic proximity Read ↗

Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validationSemantic proximity Read ↗

Identification of Highly Conserved SARS-CoV-2 Antigenic Epitopes with Wide Coverage Using Reverse Vaccinology ApproachSemantic proximity Read ↗

Identification of SARS-CoV-2 Vaccine Epitopes Predicted to Induce Long-Term Population-Scale ImmunitySemantic proximity Read ↗

T cell-mediated protection against lethal SARS-CoV-2 challenge by a synthetic long peptide vaccine targeting conserved CD4+ and CD8+ T cell epitopesSemantic proximity Read ↗

The multi-epitope vaccine prediction to combat Pandemic SARS-CoV-2, an immunoinformatic approachSemantic proximity Read ↗

Designing an efficient multi-epitope vaccine displaying interactions with diverse HLA molecules for an efficient humoral and cellular immune response to prevent COVID-19 infection.Semantic proximity Read ↗

A systemic review of T-cell epitopes defined from the proteome of SARS-CoV-2Semantic proximity Read ↗

Design of T cell epitope-based vaccine candidate for SARS-CoV-2 targeting nucleocapsid and spike protein escape variantsSemantic proximity Read ↗

Robust computational design and evaluation of peptide vaccines for cellular immunity with application to SARS-CoV-2Semantic proximity Read ↗

¿p#1 Characterization of HLA-A*11:01/A*02:01-Restricted SARS-CoV-2 T Cell Epitopes for Vaccine DesignSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.