Article

Insulin sensitization by hepatic FoxO deletion is insufficient to lower atherosclerosis in mice

2023-10-18

Abstract excerpt

<h4>Background</h4> Type 2 diabetes is associated with an increased risk of atherosclerotic cardiovascular disease. It has been suggested that insulin resistance underlies this link, possibly by altering the functions of cells in the artery wall. We aimed to test whether improving systemic insulin sensitivity reduces atherosclerosis. <h4>Methods</h4> We used mice that are established to have improved systemic in...

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Literature Corpus work: 76421f4b-9e77-5332-8dcd-2c97fac38fec
DOI: 10.1101/2023.10.14.562366

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