Article

A novel non-genetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosis

2021-11-12

Abstract excerpt

<h4>Objective</h4> Atherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients. Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new nongenetic model of inducible metabolic risk factors that mimics hyperlipidemia, hyperglycemia, or both and allows the detection of phenotypic differences dependent on the met...

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Literature Corpus work: 0010b0c6-fb48-5aea-8c74-da89c294b5a0
DOI: 10.1101/2021.11.11.468191

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