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Proliferative CD8 T-cells : A Novel Immune Microenvironmental Determinant of Outcomes in Multiple Myeloma

2025-07-03

Abstract excerpt

<title>Abstract</title> <p>Multiple myeloma (MM) remains incurable despite major therapeutic advances, and the tumor microenvironment (TME) plays an important role in disease progression. Since T-cell dysfunction is of particular importance in MM, we hypothesised that dysfunctional cytotoxic T cells may be associated with adverse outcomes. We conducted single-cell multi-omic sequencing of newly-diagnosed MM to id...

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Literature Corpus work
75cc506f-c58b-5c40-8ca0-1779e41b2ed8
DOI
10.21203/rs.3.rs-6929982/v1
Open publication

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Proliferative CD8 T-cells : A Novel Immune Microenvironmental Determinant of Outcomes in Multiple MyelomaDOI 10.21203/rs.3.rs-6929982/v1
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