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A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

2024-05-17

Abstract excerpt

<h4>ABSTRACT</h4> Multiple Myeloma (MM) remains incurable despite advances in treatment options. Although tumor subtypes and specific DNA abnormalities are linked to worse prognosis, the impact of immune dysfunction on disease emergence and/or treatment sensitivity remains unclear. We established a harmonized consortium to generate an Immune Atlas of MM aimed at informing disease etiology, risk stratification, an...

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Literature Corpus work
5a16cc78-1fb8-5adb-8863-17538edfceae
DOI
10.1101/2024.05.15.593193
Open publication

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A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myelomaDOI 10.1101/2024.05.15.593193
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